Pathology: Histology, Cytology, ROSE & Molecular Markers
Reviews sample preparation, cell block optimization, reflex testing, and communication with pathology to maximize diagnostic yield.
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Exam mapping & scope
This chapter maps to core diagnostic domains for interventional pulmonology board review: lung cancer histology and classification; cytology fundamentals; rapid on‑site evaluation (ROSE) workflow and decision‑making; tissue and cell‑block triage for immunohistochemistry (IHC), fluorescence in situ hybridization (FISH), polymerase chain reaction (PCR), next‑generation sequencing (NGS), and circulating tumor DNA (ctDNA) testing; PD‑L1 assessment and immune‑response evaluation criteria; and practical algorithms linking specimen type to molecular testing and treatment selection across adenocarcinoma, squamous, and neuroendocrine carcinomas.
Focus this round
- Specimen triage
- Testing pathways
- Communication with pathology
Interactive chapter
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